EXPLORING THE ANTIDIABETIC AND ANTIOXIDANT POTENTIAL OF NEPETA ADENOPHYTA HEDGE IN HEPG2 CELLS AND ITS PHYTOCHEMICAL STUDIES

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Published May 28, 2023
DOI: https://doi.org/10.53874/jmar.v8i0.178

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R. Ilyas
Noor-ul-Huda Public School, Eidgah, 14300-Astore, Pakistan
M. Ali
Muhammad Ali Jinnah Government Boys High School, Jutial, 15100-Gilgit, Pakistan
I. Ali
Shandong Analysis and Test Center, Qilu University of Technology, China
B. Siyo
Department of Chemistry, Tishreen University, Latakia, Syria
W. Xu
School of Food and Advanced Technology, Massey University, Palmerston North, New Zealand
A. Hussain
Department of Chemistry University of Okara, Okara, Pakistan
W. Wei
Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan-250014, China
L. Chen
Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan-250014, China
Zamarrud T.
Department of Botany, University of Karachi, Karachi-75270, Pakistan
X. Wang
Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan-250014, China

Abstract

The current study is based on the phytochemical isolation and biological activity evaluation of Nepeta adenophyta Hedge. This plant species is traditionally used for abdominal pain, kidney pain, stomach problems, urine problems, and diarrhea and is examined to control bleeding. Five compounds were isolated using column chromatography over normal silica gel from the ethanolic crude extract of Nepeta adenophyta and their structures were characterized with the help of spectroscopic techniques. In addition, the crude extract was evaluated for its antioxidant and antidiabetic potential in a human hepatoma cell line HepG2 cells and the crude extract showed good activities. The phytochemical isolation studies and the biological activities are conducted for the first time on the study sample.

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How to Cite
ILYAS, R. et al. EXPLORING THE ANTIDIABETIC AND ANTIOXIDANT POTENTIAL OF NEPETA ADENOPHYTA HEDGE IN HEPG2 CELLS AND ITS PHYTOCHEMICAL STUDIES. Journal of Mountain Area Research, [S.l.], v. 8, p. 72-81, may 2023. ISSN 2518-850X. Available at: <https://journal.kiu.edu.pk/index.php/JMAR/article/view/178>. Date accessed: 19 apr. 2024. doi: https://doi.org/10.53874/jmar.v8i0.178.
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Issue
Vol 8 (2023)
Section
Chemical Sciences
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